1. Kawada C., et al. Nutrients. 2021. Randomized, double-blind, placebo-controlled trial of 120 mg/day oral HA for 12 weeks improved hydration, elasticity, and wrinkle measures. https://www.mdpi.com/2072-6643/13/7/2220 MDPI
2. Breeman M. Journal of Drugs in Dermatology. 2025. Meta-analysis of seven RCTs shows significant improvements in skin hydration/elasticity and reduced wrinkle depth with oral HA. https://jddonline.com/oral-hyaluronic-acid-supplement-efficacy-in-skin-hydration-elasticity-and-wrinkle-depth-reduction/ JDD Online
3. Göllner I., et al. J Evid-Based Complement Altern Med. 2017. Practice/clinical study of oral HA solution improved hydration and elasticity within 20–40 days. https://journals.sagepub.com/doi/pdf/10.1177/2156587217743640 SAGE Journals
4. MedlinePlus (NIH). “Fluid and Electrolyte Balance.” Electrolytes help regulate body fluid balance, including cellular hydration. https://medlineplus.gov/fluidandelectrolytebalance.html MedlinePlus
5. Schröder J.M., et al. J Invest Dermatol. Taurine acts as an epidermal osmolyte supporting keratinocyte hydration/barrier function. https://www.sciencedirect.com/science/article/pii/S0022202X15303729 ScienceDirect
6. Alberts A., et al. Molecules. 2025. Review: vitamin C is an essential cofactor for prolyl/lysyl hydroxylases in collagen synthesis. https://www.mdpi.com/1420-3049/30/3/748 MDPI
7. Barel A., et al. J Am Acad Dermatol. 2005. 20-week RCT: choline-stabilized orthosilicic acid (10 mg Si/day) improved skin micro-relief/mechanics and reduced nail brittleness. https://www.jaad.org/article/S0190-9622(04)02898-1/fulltext jaad.org
8. Cheryan V., et al. J Inorg Biochem / related reviews. Proline/hydroxyproline and vitamin C are critical for collagen stability and biosynthesis. https://www.sciencedirect.com/science/article/pii/S0022316622106243